Author

Verónica Ramírez‐Alcántara

University of South AlabamaORCID 0000-0001-6151-2008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adam B. KeetoniD· 1 shared Anju SinghiD· 1 shared Asfar Sohail AzmiiD· 1 shared Bassel F. El‐RayesiD· 1 shared Brusi Kola· 1 shared Chandrani SarkariD· 1 shared Craig M. PowelliD· 1 shared Debanjan ChakrobortyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adam B. KeetonORCID

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2 papers

Recent·Most cited

ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma

Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, J. -W. Wang, Jeremy B. Foote, Adam B. Keeton, Xi Chen, Verónica Ramírez‐Alcántara, Thomas Holmes, Mehmet Akce, Anju Singh, Craig M. Powell, Santosh Kumar Behera, Asfar Sohail Azmi, Elmar Nurmemmedov, , Bassel F. El‐Rayes

Oral PDE10 inhibitor ADT-030 curbed KRAS-mutant pancreatic cancer growth and metastasis in mouse models, stayed active in KRAS-inhibitor-resistant cells, and shifted tumor immune profiles.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology✦ In-depth digest

Angiotensin II Type 1 Receptor Blockade Inhibits Gastric Cancer Metastasis Through Tight Junction Restoration

Sooraj Kakkat, Prabhat Suman, Sandeep Goswami, Brusi Kola, Kira Bruno, Wendy L. Frankel, Sujit Basu, Elba A. Turbat‐Herrera, Verónica Ramírez‐Alcántara, Martin J. Heslin, Joel Andrews, Paramahansa Pramanik, Chandrani Sarkar, Debanjan Chakroborty

This study shows that blocking the angiotensin II type 1 receptor reduces gastric cancer metastasis by restoring tight junctions through mechanisms involving KLF4 and TJ protein expression.

Cancer Letters · May 2, 2026Peer-reviewedCancer Biology