Author

Sarita Giri

Virginia Commonwealth UniversityORCID 0000-0001-6157-3003Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Apurva Tadimari PrabhakariD· 2 shared Claire D. JamesiD· 2 shared Iain M. MorganiD· 2 shared Jenny D Roe· 2 shared Molly L. BristoliD· 2 shared Phoebe V. Bridy· 2 shared A. NguyeniD· 1 shared Ahmed DiabiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Apurva Tadimari PrabhakarORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

E2 displacement of CIP2A from TOPBP1 activates the DNA damage response during papillomavirus life cycles

Apurva Tadimari Prabhakar, Claire D. James, A. Nguyen, Phoebe V. Bridy, Xu Wang, Ryan J. Zoldork, Jenny D Roe, Austin J. Witt, Srimanya S. Panidepu, Sarita Giri, Molly L. Bristol, Krista Dalton, Andreas Wieland, Ahmed Diab, Anthony C. Faber, , Iain M. Morgan

This paper shows E2 activates the DNA damage response by displacing CIP2A from TOPBP1, promoting viral replication and cell proliferation through ATM activation and ATR inhibition.

Cell Reports · Oct 26, 2026Peer-reviewedCancer Biology

Differentiation-Dependent Proximity Proteomics Identifies Novel Host Factors Linked to HPV16 E2 Function

Claire D. James, Aya H. Youssef, Apurva Tadimari Prabhakar, Jenny D Roe, Elinor Lu, Austin Witt, Sarita Giri, Molly L. Bristol, Phoebe V. Bridy, Xu Wang, Arjun Rijal, Charles E. Lyons, Iain M. Morgan

This study identifies novel host factors interacting with HPV16 E2 during differentiation using proximity proteomics, revealing a cooperative E2-TOPBP1-NCL axis critical for viral genome stability.

mBio · Jan 12, 2026Peer-reviewedCancer Biology