Author

Susan K. Goderie

Neural Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Sally TempleiD· 5 shared Celeste M M. KarchiD· 4 shared Steven Lotz· 4 shared Alison GoateiD· 3 shared Kathryn R. BowlesiD· 3 shared Taylor B. BertucciiD· 3 shared David C. Butler· 2 shared Farhad FarjoodiD· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersNeuroscience

Sally TempleORCID

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Author profile →

5 papers

Recent·Most cited

Fully Human Bifunctional Intrabodies Achieve Graded Reduction of Intracellular Tau and Rescue Survival of MAPT Mutation iPSC-derived Neurons

Lianna D’Brant, Natasha Rugenstein, Su Kyoung Na, Michael J. Miller, Timothy F. Czajka, Nicole Trudeau, Emily M Fitz, Lindsay Tomaszek, Elizabeth S. Fisher, Ethan Mash, Shona Joy, Steven Lotz, Susan M. Borden, Katherine Stevens, Susan K. Goderie, , David C. Butler

The paper develops fully human bifunctional anti-tau intrabodies that reduce intracellular tau and improve neuronal survival in disease-associated mutations.

bioRxiv · May 28, 2024 · PreprintNeuroscience

Adult Mouse Leptomeninges Exhibit Regional and Age-related Cellular Heterogeneity and Gene Expression Differences Implicating Mental Disorders

Christina A. Allen, Susan K. Goderie, Mo Liu, Thomas R. Kiehl, Farhad Farjood, Yue Wang, Nathan C. Boles, Sally Temple

The paper analyzes regional and age-related differences in adult mouse leptomeninges using snucRNA-seq, revealing gene expression patterns linked to mental disorders.

bioRxiv · Sep 10, 2023 · PreprintNeuroscience

Integrated Manufacturing Platform for Cortical Organoids Reveals Early Phosphatase and Prefoldin Dysregulation in MAPT V337M Neurons

Taylor B. Bertucci, Kathryn R. Bowles, Steven Lotz, Shiraz Bheda, Le Qi, Farhad Farjood, Katherine Whitton, Susan K. Goderie, Susan M. Borden, Amelia Rossi, Kate Tubbesing, Chiara Pedicone, Laura Maria Oja, Keith Lane, Ryan Lotz, , Sally Temple

The paper develops a scalable cortical organoid platform with quality control metrics and identifies early dysregulation of phosphatase and prefoldin genes in FTD-tau neurons.

bioRxiv · Jul 11, 2023 · PreprintNeuroscience

Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutation.

Kathryn R. Bowles, M. Catarina Silva, Kristen R. Whitney, Taylor B. Bertucci, Jacob C. Garza, Nathan C. Boles, Kevin H. Strang, Sidhartha K. Mahali, Jacob A. Marsh, Cynthia Chen, Derian A. Pugh, Yiyuan Liu, Joshua E. Berlind, Jesse D. Lai, Susan K. Goderie, , Sally Temple

This study shows that glutamatergic dysfunction occurs before neuron loss in cerebral organoids with MAPT mutations, suggesting therapeutic targets for FTD.

bioRxiv · Feb 3, 2021 · PreprintNeuroscience

Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

James A. Gregory, Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern, Natalie Barretto, Nadine Schrode, Güney Akbalık, Kristy Kang, Esther Cheng, Kathryn R. Bowles, Steven Lotz, Susan K. Goderie, Celeste M M. Karch, , Hemali P. Phatnani

The paper extends the RiboTag system for cell-type specific RNA depletion in vitro, showing variable efficiency across replicates.

Cells · Jun 5, 2020Peer-reviewedGenomics