MicrobiologybioRxivPreprint
Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency
Sereina O. Sutter, Sarah Jetzer, Anouk Lkharrazi…·Cornel Fraefel
The paper shows that inducing autophagy with hyperosmotic sucrose enhances AAV2 transduction efficiency through a non-canonical pathway, distinct from the PI3K-III-dependent mechanism.