Author
University of California, San FranciscoORCID 0000-0001-6211-3498Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Danh D. Truong, Justin W. Magrath, Kevin A. Murgas…·Joseph Aloysius Ludwig
This study identifies DSRCT-specific neogenes regulated by the EWS::WT1 fusion protein and shows their potential as biomarkers and therapeutic targets in desmoplastic small round cell tumors.
Siyu Chen, Daniel Markett, Mehran Karimzadeh…·Hani Goodarzi
The paper identifies ZZEF1 as a tRNA-specific transcription factor that suppresses breast cancer metastasis by regulating tRNA-LysUUU expression and affecting codon-specific translation.
Matvei Khoroshkin, Arsenii O. Zinkevich, Elizaveta Aristova…·Hani Goodarzi
This paper introduces PARADE, a generative AI framework for designing mRNA UTRs with cell-type specificity, showing improved therapeutic efficacy in preclinical models.
Matvei Khoroshkin, Andrey Buyan, Martin Dodel…·Hani Goodarzi
The paper systematically identifies post-transcriptional regulatory modules by integrating multimodal data on RBP interactions and functions.