Zhifang Chen

This paper demonstrates whole-brain in vivo base editing in mice to reverse autistic-like behaviors by correcting a mutation in the MEF2C gene.

This study edits PINK1 and DJ-1 genes in adult monkey brains using AAV-delivered CRISPR/Cas9, resulting in Parkinsonian symptoms and pathology.

This study uses in vivo CRISPR/Cas9 to edit MECP2 in adolescent rhesus monkeys, resulting in autistic-like behaviors.