Longbao Lv

This study develops GrB-CAR T cells targeting mHSP70 to eliminate CTCs and inhibit metastasis in solid tumors.

circAge compiles aging-associated circRNA data from 7 species and 21 tissues, identifying 413,378 unique circRNAs and their conservation, interactions, and coding potential.

This paper develops a tree shrew Parkinson's disease model that replicates key clinical and pathological features of PD, offering a cost-effective alternative to primate models.

This study shows that light intensity non-linearly affects ocular axial length growth in rhesus monkeys, with medium intensity light causing greater growth than low or high intensity light.

This study shows that maternal separation in young rhesus monkeys can induce three core ASD symptoms, suggesting early environmental adversity contributes to ASD pathogenesis.

This study edits PINK1 and DJ-1 genes in adult monkey brains using AAV-delivered CRISPR/Cas9, resulting in Parkinsonian symptoms and pathology.

This study uses in vivo CRISPR/Cas9 to edit MECP2 in adolescent rhesus monkeys, resulting in autistic-like behaviors.