Tian‐Lin Cheng

The paper shows microglia preserve fear memory by selectively pruning extinction-ensemble synapses through local signaling cues during memory retrieval.

The paper identifies CALN1 as a key schizophrenia gene by showing its role in disrupting forebrain development and causing hallucination-like behavior in mice.

This paper demonstrates whole-brain in vivo base editing in mice to reverse autistic-like behaviors by correcting a mutation in the MEF2C gene.

This study edits PINK1 and DJ-1 genes in adult monkey brains using AAV-delivered CRISPR/Cas9, resulting in Parkinsonian symptoms and pathology.

This study uses in vivo CRISPR/Cas9 to edit MECP2 in adolescent rhesus monkeys, resulting in autistic-like behaviors.