Heewon Seo

The paper identifies reproducible transcriptional modules across glioblastoma datasets, showing cross-cohort consistency and biological relevance.

The paper investigates sex differences in parvalbumin interneurons in healthy mice, finding females have fewer but more active and plastic inhibitory neurons in the retrosplenial cortex.

The paper identifies sex-dependent impairments in parvalbumin interneurons in the retrosplenial cortex as a cause of cognitive deficits in Alzheimer's disease and suggests targeting these neurons as a therapeutic strategy.

This study evaluates gene representation in spatial transcriptomics using pre-designed panels and introduces a Coverage Index to assess gene signature coverage across datasets.

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.

mosaicMPI integrates multi-omics data across cohorts to reveal biological themes and enable rapid mapping of new datasets.

The paper introduces a cloud-based platform called ORCESTRA for reproducible processing and sharing of multimodal biomedical data in a FAIR manner.