Author

Bo Young Ahn

University of CalgaryORCID 0009-0002-4583-8950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Derya SarginiD· 2 shared Dylan J. TerstegeiD· 2 shared Heewon SeoiD· 2 shared Jonathan R. EppiD· 2 shared Aadarsh Shrestha· 1 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Ayan ChandaiD· 1 shared Beruwalage Hirushika Fernando· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Derya SarginORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Eukaryotic Initiation Factor 5B (eIF5B)-Driven Translational Control Impacts Oral Squamous Cell Carcinoma Pathophysiology

Pavan Lakshmi Narasimha, Jinay Patel, Ayan Chanda, Veda Hegde, Beruwalage Hirushika Fernando, Hannah Stephenson, Rebecca Mubaya, Aadarsh Shrestha, Steven C. Nakoneshny, Bo Young Ahn, Thomas Wayne Matthews, Shamir P. Chandarana, Robert D. Hart, Joseph Clyde Dort, Martin D. Hyrcza, , Nehal Thakor

This study shows that eIF5B is crucial for OSCC cell survival by enabling non-canonical translation of pro-survival mRNAs, and its inhibition reduces tumor growth and sensitizes cells to apoptosis.

bioRxiv · Feb 2, 2026 · PreprintCancer Biology

Inhibitory Circuit Compensations in Female and Male Mice: Increased Synaptic Output Offsets Reduced Parvalbumin Interneuron Density

Nadia Khoshbaf Khiabanian, Dylan J. Terstege, Shi Chen Xu, Bo Young Ahn, Heewon Seo, Derya Sargin, Jonathan R. Epp

The paper investigates sex differences in parvalbumin interneurons in healthy mice, finding females have fewer but more active and plastic inhibitory neurons in the retrosplenial cortex.

bioRxiv · May 20, 2025 · PreprintNeuroscience

Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease

Dylan J. Terstege, Yi Ren, Bo Young Ahn, Heewon Seo, Kabirat Oluwaseun Adigun, Alzheimer’s Disease Neuroimaging Initiative, Liisa A.M. Galea, Derya Sargin, Jonathan R. Epp

The paper identifies sex-dependent impairments in parvalbumin interneurons in the retrosplenial cortex as a cause of cognitive deficits in Alzheimer's disease and suggests targeting these neurons as a therapeutic strategy.

Science Advances · Apr 30, 2025Peer-reviewedNeuroscience