Author

Francesco Antonio Tucci

University of MilanORCID 0000-0001-6247-5392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Daniela TosoniiD· 2 shared Maria Grazia Filippone· 2 shared Salvatore PeceiD· 2 shared Adrian BiddleiD· 1 shared Alessandro SarcinellaiD· 1 shared Alessia LamolinaraiD· 1 shared Alex L. Nigg· 1 shared Andrea Scavuzzo· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Daniela TosoniORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 18, 2026

p140Cap enhances breast cancer chemosensitivity by limiting an ABCC1-enriched stem-like compartment via β-Catenin inhibition

Andrea Scavuzzo, Matteo Poncina, Alessia Lamolinara…·Vincenzo Salemme

This study shows p140Cap improves chemotherapy response in breast cancer by reducing stem-like cells and enhancing drug retention through β-Catenin inhibition.

1 citation

humanbulk RNA-seq

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Cancer BiologyJNCI Journal of the National Cancer InstitutePeer-reviewedMar 20, 2025

A tug-of-war between the NuRD and SWI/SNF chromatin remodelers regulates the coordinated activation of Epithelial-Mesenchymal Transition and inflammation in oral cancer.

Roberto Stabile, Francesco Antonio Tucci, Mathijs P. Verhagen…·Riccardo Fodde

The paper shows that competition between NuRD and SWI/SNF chromatin remodelers regulates epithelial-mesenchymal plasticity and inflammation in oral cancer, with CDK2AP1 loss promoting pro-inflammatory responses and macrophage recruitment.

4 citations

humanbulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedDec 3, 2024

Loss of the tumor suppressor NUMB drives aggressive bladder cancer through hyperactivation of a RhoA/ROCK/YAP signaling circuitry

Francesco Antonio Tucci, Rosa Pennisi, Damiano Cosimo Rigiracciolo…·Salvatore Pece

This study identifies Numb loss as a driver of aggressive bladder cancer through hyperactivation of the RhoA/ROCK/YAP signaling pathway, proposing a 27-gene signature for clinical stratification.

14 citations

humanbulk RNA-seq

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