Author

Fatih Noyan

Medizinische Hochschule HannoverORCID 0000-0001-6250-8692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Elmar JaeckeliD· 2 shared Julia K. PolanskyiD· 2 shared Mingxing Yang· 2 shared Viktor GlaseriD· 2 shared Agnes BonifaciusiD· 1 shared Artemis Gavriil· 1 shared Bader Zarrouki· 1 shared Britta Eiz‐VesperiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Elmar JaeckelORCID

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2 papers

Recent·Most cited

ImmunologyMolecular TherapyPeer-reviewedFeb 3, 2025

Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer

Weijie Du, Fatih Noyan, Oliver McCallion…·Dimitrios L. Wagner

This paper develops a non-viral CRISPR-Cas12a method to redirect Tregs with CARs by integrating an antigen-binding domain into the CD3 epsilon gene, showing improved antigen-specific function and graft protection in a mouse model.

17 citationstop 4%

humanCITE-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 12, 2024

ENTPD3-specific CAR Regulatory T cells for Local Immune Control in T1D

Tom Pieper, Tobias Riët, Valerie Saetzler…·Elmar Jaeckel

This paper develops ENTPD3-specific CAR Tregs to control T1D by targeting beta cells and shows their efficacy in preventing disease progression in a mouse model.

6 citations

mouseexperimental assay

𝕏 PostBluesky