Author

Gary H. Perdew

Pennsylvania State UniversityORCID 0000-0001-6288-8445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metabolomics· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

Iain A. MurrayiD· 3 shared Abigail T. Armstrong· 1 shared Abubaker PataniD· 1 shared Adrián JinichiD· 1 shared Andrés Mauricio Caraballo‐RodrígueziD· 1 shared Andrew D. PattersoniD· 1 shared Andrew J. AnnaloraiD· 1 shared Byeong‐Seon JeongiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

Iain A. MurrayORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 15, 2026

Alkamines reveal a hidden layer of steroid and drug metabolism

Julius Agongo, Subshaskar R Panga, Shipei Xing…·Pieter C. Dorrestein

The paper identifies alkamines as a previously hidden class of metabolites formed via reductive amination, revealing significant gaps in metabolomics and drug metabolism understanding.

1 citation

multiple speciesmetabolomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 14, 2026

Interkingdom glycine conjugates of indole-3-carboxylates are Ah receptor ligands

Ethan W. Morgan, Andrew J. Annalora, Denise M. Coslo…·Gary H. Perdew

The paper identifies glycine-conjugated indole-3-carboxylates as AHR ligands, showing human-specific activation and microbial/host-mediated metabolism.

DOI 10.64898/2026.02.13.705761

mousemetabolomics

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MicrobiologybioRxivPreprintSep 25, 2025

Fusobacterium nucleatum produces previously unappreciated AHR-activating metabolites and promotes CRC cell proliferation via the AHR-TERT axis

Kyoung‐Jae Won, Pei-Ru Jin, Lydia Davis…·Hyunyoung Jeong

This study identifies Fusobacterium nucleatum-produced indole metabolites that activate the AHR-TERT axis, promoting CRC cell proliferation and revealing FTIN as a potential biomarker.

3 citations

humanmetabolomics

𝕏 PostBluesky