Gauri Deák

This study investigates the role of H2A.Z-H2B.V nucleosomes in transcription initiation in Trypanosoma brucei, revealing their unique structural and functional properties.

The paper identifies conserved structural folds used by pathogens across all domains of life to evade immune responses.

This study determines the structure of H3.V-H4.V nucleosomes in Trypanosoma brucei and shows how these variants promote nucleosome plasticity in repressed chromatin.

This study determines the structure and function of KKT23, a kinetochore acetyltransferase in trypanosomes, showing it acetylates histone H2A and interacts with KKT22.

The paper uses missense variant depletion patterns to identify functional sites in ARID family proteins and reveals sub-functionalization through domain-level comparisons.