Christina Redfield

This study shows that the KKT2 CL domain binds histone H3 N-terminus and that methylation of this region disrupts binding, suggesting a mechanism for kinetochore assembly in kinetoplastids.

This study shows YdbL modulates YdbH-YnbE bridge formation in E. coli to maintain outer membrane homeostasis by interacting with YnbE and preventing its degradation.

This study reveals how DNA-induced conformational changes in SPRTN relieve its auto-inhibitory effect on protease activity, enabling efficient DPC proteolysis.

This study determines the structure of the Entamoeba histolytica Gal/GalNAc lectin, revealing its carbohydrate binding mechanism and antibody epitope, which informs vaccine development.

This study identifies a ubiquitin-binding domain in SPRTN that enhances its proteolytic activity towards polyubiquitinated DNA-protein crosslinks.

This study determines the structure and function of KKT23, a kinetochore acetyltransferase in trypanosomes, showing it acetylates histone H2A and interacts with KKT22.

This study examines the transition state of DNA binding in disordered bZIP domains and finds it resembles the unbound state, challenging predictions of disorder-mediated rate enhancement.