Author
The Jackson Laboratory for Genomic MedicineORCID 0000-0001-6307-016XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Youri Hoogstrate, Santoesha A. Ghisai, Levi van Hijfte…·Pim J. French
The paper identifies DNA methylation changes during IDH-mutant glioma progression, links them to TET enzyme activity, and develops a methylation-based grading system that outperforms WHO grading.
Tamrin Chowdhury, C. Mircea S. Tesileanu, Emre Kocakavuk…·Roel G.W. Verhaak
This study identifies genetic changes in IDH-mutant gliomas that correlate with treatment response and tumor evolution using longitudinal genomic data from 206 patient samples.
Tathiane Maistro Malta, Thaís S. Sabedot, Natalia S. Morosini…·Peter S. LaViolette
This study analyzes the epigenetic evolution of IDH1-mutant and IDH1-wildtype gliomas under treatment, showing IDHmut tumors undergo epigenomic changes resembling IDHwt tumors, with implications for treatment strategies.