Author

Jan Wenzel

German Centre for Cardiovascular ResearchORCID 0000-0001-6313-2439Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Markus SchwaningeriD· 2 shared Ákos MenyhártiD· 1 shared Aleyna M. Diniz· 1 shared Anne-Sophie Gutt· 1 shared Beate Lembrich· 1 shared Cathrin Elly HanseniD· 1 shared Dimitrios Spyropoulos· 1 shared Dorothea ZiemensiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Markus SchwaningerORCID

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2 papers

Recent·Most cited

NeuroscienceEBioMedicinePeer-reviewedMay 18, 2026

Gαq/11 signalling counteracts endothelial dysfunction in the brain and protects cognition in aged mice

Dimitrios Spyropoulos, Lena Kleindienst, Phillip Ehrich…·Jan Wenzel

This study shows that Gαq/11 signaling in brain endothelial cells prevents endothelial dysfunction and cognitive decline in aged mice by maintaining vascular reactivity and preventing blood-brain barrier disruption.

DOI 10.1016/j.ebiom.2026.106283

mouseexperimental assay

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Developmental BiologyNature BiotechnologyPeer-reviewedNov 13, 2025

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue

Mostafa Aakhte, G.A. Müller, Lennart Roos…·Jan Huisken

This paper introduces a high-speed light sheet microscope with isotropic sub-micron resolution for cleared tissue imaging, achieving 850 nm resolution across 1 cm3 samples.

12 citationstop 4%

zebrafishmouse

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