Federica Mosti

The paper identifies 1,596 Consensus HAQERs by aligning T2T assemblies, showing they are rapidly evolved regions with mutation signatures, regulatory functions, and disease associations.

The paper shows human-specific enhancer HAR1984 promotes neurogenesis by altering chromatin interactions and gene regulation in cortical organoids and mice.

The paper shows human-specific variants in HARE5 enhance enhancer activity, promoting progenitor proliferation and contributing to human cortical expansion.

This study shows EIF4A3 controls axonal tract formation by directly regulating microtubule dynamics in neurons, independent of its RNA-binding function.

This paper shows that depletion of Drosophila CNBP causes age-dependent locomotor defects linked to reduced polyamine metabolism and ODC levels, which can be rescued by polyamine supplementation or ODC overexpression.