Marta Marzullo

This study investigates the distinct toxic effects of QAGR and PACL peptides in Drosophila, showing they impair nucleolar function and autophagy or alter stress granule dynamics, contributing to DM2 pathogenesis.

This study identifies Caspase-8 as a novel promoter of Homologous Recombination Repair in glioblastoma, enhancing DNA repair and resistance to ionizing radiation.

This study shows that asp and Sas4 genes in Drosophila affect nuclear structure, chromatin organization, and genome stability, contributing to microcephaly pathogenesis.

This study shows that cGAS-STING contributes to premature aging in telomerase-deficient zebrafish by promoting senescence and inflammation, and its absence rescues aging-related phenotypes.

The paper shows that Su(var)3-9 increases H3K9 methylation on the TDP-43 promoter with age, leading to reduced TDP-43 expression and neurodegeneration in Drosophila, mice, and humans.

The paper uses spatially resolved transcriptomics to identify innervation-responsive functional clusters in skeletal muscle and shows changes in atrophic signaling and polyamine metabolism upon denervation.

The paper identifies cell- and stage-specific transcriptional signatures in Drosophila neurons, glia, and hemocytes, revealing that developmental stage significantly influences gene expression patterns.

This paper shows that depletion of Drosophila CNBP causes age-dependent locomotor defects linked to reduced polyamine metabolism and ODC levels, which can be rescued by polyamine supplementation or ODC overexpression.

This paper shows Hmr and Lhr are needed for sister chromatid detachment during anaphase, not centromere function, in Drosophila melanogaster.