Hanzhi Zhao

This study shows that a human-specific gene duplication alters cortical network dynamics in mice, improving task performance through reconfigured interhemispheric correlations and distributed encoding.

The paper shows human-specific variants in HARE5 enhance enhancer activity, promoting progenitor proliferation and contributing to human cortical expansion.

This study investigates how mTOR inhibition reverses glioma-induced changes in excitatory neurons, showing effects on mRNA, dendritic spines, and neuronal activity.

This study shows that the human-specific gene SRGAP2C increases cortico-cortical connectivity and improves sensory processing and behavioral performance in mice.

This study tracks glioma progression in mice, showing decreased neuronal synchrony, disrupted neurovascular coupling, and seizure-related hypoxia in infiltrated cortex.