Federica A. Falconio

This paper shows that depletion of Drosophila CNBP causes age-dependent locomotor defects linked to reduced polyamine metabolism and ODC levels, which can be rescued by polyamine supplementation or ODC overexpression.

The paper investigates the role of maternally inherited piRNAs in silencing transposons in early Drosophila embryos by analyzing their impact on heterochromatin formation and transposon expression.

The paper identifies Nxf2 and Nxt1 as factors required for piRNA-guided co-transcriptional silencing of transposons in Drosophila, showing their interaction with Panx and role in repressive chromatin formation.

The paper identifies Daedalus and Gasz as mitochondrial factors that recruit Armitage to mitochondria, facilitating piRNA precursor processing by linking nuage/Yb-body and mitochondrial biogenesis machinery.