Author
Icahn School of Medicine at Mount SinaiORCID 0000-0001-6319-0372Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis…·Miriam Mérad
This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.
Samarth Hegde, Bruno Giotti, Brian Y. Soong…·Miriam Mérad
The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.
Pauline Hamon, Matthew D. Park, Jessica Le Bérichel…·Miriam Mérad
The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.
Emir Radkevich, Darwin D’souza, Raphaël Mattiuz…·Vladimir Roudko
The paper benchmarks deconvolution tools for spatial transcriptomic data and introduces a novel pipeline to analyze tissue microenvironment dynamics.
Bruno Giotti, Komal Dolasia, William Zhao…·Alexander M. Tsankov
This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.