Author

Paula I Seoane

Manchester Academic Health Science CentreORCID 0000-0001-6323-5470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Abigail Owen· 1 shared Antony D. AdamsoniD· 1 shared Billie J. MatchettiD· 1 shared Christopher HoyleiD· 1 shared Dalan BaileyiD· 1 shared David BroughiD· 1 shared David StirlingiD· 1 shared Gloria López‐CastejóniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Abigail Owen

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 21, 2025

Lysosome positioning affects NLRP3 inflammasome activation

Billie J. Matchett, Jack Green, Paula I. Seoane…·David Brough

This study investigates how lysosome positioning affects NLRP3 inflammasome activation in HeLa and macrophage cells, finding that peripheral lysosome positioning enhances inflammasome activation.

2 citations

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintJan 4, 2019

Viral infection enhances vomocytosis of intracellular fungi via Type I interferons

Paula I Seoane, Leanne M. Taylor-Smith, David Stirling…·Robin C. May

This paper shows that viral infection increases vomocytosis of Cryptococcus neoformans by macrophages through type-I interferons.

DOI 10.1101/512293

humanproteomics

𝕏 PostBluesky