Athea Vichas

ALPINE classifies gene-editing outcomes from long-read amplicon sequencing into 10+ categories, including DNA repair vector integrations, with high accuracy.

This study shows that USP9X stabilizes RIT1 protein and that its depletion reduces RIT1 abundance and sensitizes cells to EGFR inhibitors.

This study identifies unique vulnerabilities of oncogenic EGFR, KRAS, and RIT1 in lung cancer through integrative analysis of CRISPR screens and drug sensitivity data.