Jason R. Rock

This study investigates how pirfenidone and nintedanib affect the growth and differentiation of human alveolar type 2 cells in organoid cultures, revealing differences in their impact on surfactant protein C expression and cell identity.

This study shows that blocking OSM and IL-6 reduces fibrosis and inflammation in pulmonary fibrosis by targeting their shared receptor and distinct pathways.

The paper introduces SCimilarity, a metric learning framework for querying and comparing single-cell RNA-seq data across the human body, revealing commonalities in fibrosis-associated macrophages.

This study shows that cochlear spontaneous activity during development is crucial for proper auditory circuit maturation, affecting frequency tuning and neural gain.