Martin Ott

This study engineers yeast to express a tethered respiratory supercomplex, revealing its role in optimizing electron flux and metabolic plasticity through substrate-specific interactions.

The paper investigates how mitochondrial translational activators (TAs) facilitate transcript-specific translation initiation by aligning mRNAs at the small mitoribosomal subunit.

The paper identifies a molecular switch at the yeast mitoribosomal tunnel exit that regulates cytochrome b synthesis by mediating interactions between translational activators and assembly factors.

This paper uses machine learning to integrate proteome and metabolome data, revealing new protein-metabolite connections and gene functions in yeast.