Andreas Carlström

Bioengineered yeast tethered respiratory supercomplexes reveal mechanisms governing efficient substrate utilization

This study engineers yeast to express a tethered respiratory supercomplex, revealing its role in optimizing electron flux and metabolic plasticity through substrate-specific interactions.

Translational activators align mRNAs at the small mitoribosomal subunit for translation initiation

The paper investigates how mitochondrial translational activators (TAs) facilitate transcript-specific translation initiation by aligning mRNAs at the small mitoribosomal subunit.

A molecular switch at the yeast mitoribosomal tunnel exit controls cytochrome b synthesis

The paper identifies a molecular switch at the yeast mitoribosomal tunnel exit that regulates cytochrome b synthesis by mediating interactions between translational activators and assembly factors.