Author

Wen Gu

Jewish General HospitalORCID 0000-0001-9765-7153Unclaimed ORCID profile · follow to get notified of new preprints

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Wen Gu1 paper · Duke Kunshan University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

ALBERT KOULMANiD· 1 shared Benjamin JenkinsiD· 1 shared Bernhard MichalkeiD· 1 shared Carine FillebeeniD· 1 shared Christoph H. BorchersiD· 1 shared Darren M. BlackburniD· 1 shared Éric BonneiliD· 1 shared Gary SweeneyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

ALBERT KOULMANORCID

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1 paper

Recent·Most cited

PathologyJCI InsightPeer-reviewedJan 6, 2026

IRP1 deficiency alters mitochondrial metabolism and protects against metabolic syndrome pathologies

Wen Gu, Nicole Wilkinson, Carine Fillebeen…·Kostas Pantopoulos

This study shows that IRP1 deficiency in mice leads to metabolic changes that protect against metabolic syndrome by altering mitochondrial function and improving insulin sensitivity.

2 citations

mouseproteomics

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