Cell BiologybioRxivPreprint
Mitochondrial Double-Stranded RNA Triggers Ferroptosis via PKR-ISR Signaling in Renal Ischemia-Reperfusion Injury
Richie Justin, Maria Sophia Criste, Soyoung Park…·Jaeseok Han
This study identifies mitochondrial dsRNA-PKR-ISR signaling as a driver of ferroptosis in renal ischemia-reperfusion injury, showing that targeting this pathway reduces ferroptosis and preserves kidney function.
DOI 10.64898/2026.01.19.700463