Author

Paola Defilippi

University of TurinORCID 0000-0001-6427-4906Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Alec S.T. SmithiD· 1 shared Alessandro BerteroiD· 1 shared Alessandro SarcinellaiD· 1 shared Alessia LamolinaraiD· 1 shared Andrea Scavuzzo· 1 shared Anne‐Marie TassiniD· 1 shared Barbara BellettiiD· 1 shared Daniela TavernaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperSynthetic Biology

Alec S.T. SmithORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintOct 27, 2026

Genetic control couples TGFβ-independent pluripotent stem cell renewal to deterministic forward programming across germ layers

Sveva Bottini, Francesca Amodeo, Divyashree Avnoor…·Alessandro Bertero

This paper introduces GERALT, a genetic circuit that enables TGFβ-independent hiPSC renewal and inducible lineage programming, improving differentiation efficiency and reducing medium complexity.

DOI 10.64898/2026.10.25.761636

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 18, 2026

p140Cap enhances breast cancer chemosensitivity by limiting an ABCC1-enriched stem-like compartment via β-Catenin inhibition

Andrea Scavuzzo, Matteo Poncina, Alessia Lamolinara…·Vincenzo Salemme

This study shows p140Cap improves chemotherapy response in breast cancer by reducing stem-like cells and enhancing drug retention through β-Catenin inhibition.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintOct 30, 2025

KIAA1217/SKT and its paralog p140Cap are centrosomal proteins that regulate ciliogenesis through Src family signaling pathway.

Logan Greibill, Lucie Raimbourg, Hugo Siegfried…·Anne‐Marie Tassin

DOI 10.1101/2025.10.30.685566

humanexperimental assay

𝕏 PostBluesky