Author

Miwa Sasai

Center for Infectious Disease Education and Research, The University of OsakaORCID 0000-0001-6440-3958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Masahiro YamamotoiD· 3 shared Yuta TachibanaiD· 2 shared Akio TsuruiD· 1 shared Daisuke OriiD· 1 shared Daron M. StandleyiD· 1 shared Dominique Soldati‐FavreiD· 1 shared Eizo TakashimaiD· 1 shared Haruna Okude· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Masahiro YamamotoORCID

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3 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedApr 4, 2026

An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells

Yuta Tachibana, Xue Gu, Miwa Sasai…·Masahiro Yamamoto

The paper identifies MIC11 as an essential gene for Toxoplasma gondii egress, showing it interacts with PLP1 to disrupt host cell membranes.

DOI 10.1038/s41467-026-71423-x

experimental assaygenetic perturbation / CRISPR

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 20, 2025

Gelsolin Counteracts ER Stress-Driven Inflammatory Circuits in Psoriasis-like Dermatitis

Daisuke Ori, Haruna Okude, Riko Konishi…·Taro Kawai

This study identifies Gelsolin as a regulator of ER stress in psoriasis-like dermatitis, showing it counteracts inflammatory circuits driven by IMQ-induced organelle stress.

DOI 10.1101/2025.11.20.689413

humanbulk RNA-seq

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MicrobiologymBioPeer-reviewedJul 31, 2024

In vivo CRISPR screens identify novel virulence genes among proteins of unassigned subcellular localization in Toxoplasma

Yuta Tachibana, Miwa Sasai, Masahiro Yamamoto

The paper uses in vivo CRISPR screens to identify virulence genes among Toxoplasma proteins with unassigned subcellular localizations, finding two essential genes conserved in Apicomplexa.

6 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky