Eizo Takashima

The paper identifies MIC11 as an essential gene for Toxoplasma gondii egress, showing it interacts with PLP1 to disrupt host cell membranes.

This study identifies Pfs230 Domain 12 as a potent malaria transmission-blocking vaccine candidate that induces antibodies reducing parasite transmission to mosquitoes.

This study shows that PfDGAT is essential for Plasmodium falciparum survival by maintaining phospholipid homeostasis, regulating sexual differentiation, ER stress, and cytoadhesion.

This study evaluates how genetic diversity in Plasmodium vivax antigens affects serological markers for malaria exposure and finds that using multiple antigens can improve detection accuracy.

The paper determines the structure of the Pfs230:Pfs48/45 complex bound to transmission-blocking antibodies, revealing molecular interactions and epitopes that inform vaccine development.

This study uses ultrastructural expansion microscopy to visualize RESA in malaria parasite dense granules, confirming its localization and facilitating the identification of novel DG proteins.

The paper identifies and validates a panel of 8 P. vivax proteins whose IgG antibody responses can detect recent exposure to P. vivax infections within the prior 9 months with 80% sensitivity and specificity.