Xuemeng Zhou

This study shows SALL2 restricts trophectoderm identity by maintaining repressive chromatin at TEAD4-bound loci, preventing TE lineage commitment in human pluripotent stem cells.

This study shows transposable elements contribute significantly to 3D genome structure by mediating chromatin contacts through specific transcription factors.

This study examines TE expression and sub-cellular dynamics during hPSC differentiation to endoderm, mesoderm, and ectoderm lineages, revealing lineage-specific TE expression patterns and chromatin associations.

The paper investigates how SARS-CoV-2 infection alters the transcriptome and epigenome at the maternal-fetal interface, linking these changes to adverse pregnancy outcomes.

This study shows that replication timing (RT) is essential for maintaining the global epigenetic state and genome compartmentalization in human cells, with RIF1 playing a central role in this process.