Vassilis Pachnis

The paper shows that different luminal nutrients activate distinct calcium responses in submucosal and myenteric neurons of the mouse small intestine.

The paper maps the regulatory landscape of neuronal and glial differentiation in the enteric nervous system using single-cell RNA sequencing and identifies gene modules and epigenetic memory associated with neurogenesis and gliogenesis.

This study shows zebrafish enteric glia can proliferate and generate enteric neurons, similar to brain neural stem cells, and are regulated by Notch signaling.

The paper shows microbiota induce AhR in enteric neurons, enabling them to respond to environmental signals.

The paper shows that apoptosis of inhibitory interneurons in the cortex is regulated by neuronal activity and can be modulated to adjust their numbers.