Malick M. Gibani

This study shows that typhoid toxin from Salmonella Typhi triggers DNA damage responses, leading to antimicrobial effects like lysozyme secretion that inhibit bacterial virulence.

The paper characterizes two Salmonella Typhimurium strains for a first-in-human challenge model, confirming their genomic and phenotypic stability post-manufacture.

The paper identifies genetic variants and HLA types associated with susceptibility to enteric fever in human volunteers challenged with Salmonella.

The paper identifies a host gene signature using machine learning to distinguish enteric fever from other febrile diseases with high accuracy.