BiochemistryJournal of Molecular BiologyPeer-reviewed
Sequence engineering at non-motif modulator residues yields a peptide that effectively targets a single PDZ protein in a disease-relevant cellular context
Jeanine F. Amacher, Patrick R. Cushing, Lars Vouilleme…·Dean R. Madden
The paper engineers a peptide that selectively targets a single PDZ domain in a cystic fibrosis model, enhancing chloride efflux.
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