Esben Lorentzen

This study reveals a communication axis between motile cilia, rootlets, and mitochondria in respiratory epithelium, enhancing ciliary motility and ATP production.

This study identifies a U-box-like domain in IFT172 that mediates ciliary signaling and protein stability, linking it to ciliopathy pathogenesis.

This study uses human stem cell models to investigate IFT140 variants causing retinal dystrophy and identifies eupatilin as a potential therapeutic for cilia defects.

This paper identifies NBCn1 as a ciliary membrane component that regulates ciliary length and Sonic hedgehog signaling through interactions with DYNLL1 and SUFU.

The paper introduces Synapse Gigamapper, a protein language model that identifies synaptic localization motifs and reveals SERCA's role in excitatory synapses.

The paper identifies variants in PRPF8 and related genes associated with CAKUT, showing their role in splicing and ciliogenesis through functional experiments.