Tomer Milo

This study shows that fentanyl interacts with the HPA axis over different timescales, with adrenal remodeling encoding stress history to influence fentanyl-seeking behavior.

This study identifies five classes of endocrine circuits in humans, revealing shared structural and regulatory principles across 43 hormone systems.

The paper uses a mathematical model of the HPA axis to show that only CRH-targeting drugs can lower long-term cortisol in mood disorders, while other targets fail due to gland-mass compensation.

This study measures longitudinal cortisol levels in bipolar disorder using hair samples and links cortisol dynamics to mood episodes through mathematical modeling.

This paper models autoimmune disease flares as excitable dynamics, showing how stochastic events trigger relapses and how regulatory cells influence their frequency.

The paper analyzes health records to show seasonal patterns in human hormones, finding that effector hormones peak in winter-spring while upstream pituitary hormones peak in summer, suggesting a circannual clock mechanism.