Author

Prem Prasad Lamichhane

The University of Texas Medical Branch at GalvestonORCID 0000-0001-6497-6836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Parimal SamiriD· 2 shared Aditi· 1 shared Aditi Aditi· 1 shared Alfredo G. TorresiD· 1 shared Ashok K. ChopraiD· 1 shared Blake H. NeiliD· 1 shared Paul B. KilgoreiD· 1 shared Xuping XieiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

Parimal SamirORCID

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2 papers

Recent·Most cited

ImmunologyScientific ReportsPeer-reviewedJul 16, 2026

Pharmacological interrogation of crosstalk between TLR signaling and stress granules reveals a compound with antiviral effect.

Aditi, Prem Prasad Lamichhane, Xuping Xie, Parimal Samir

The paper screens TLR signaling inhibitors to identify compounds affecting stress granules and finds PPM18, which inhibits Influenza A Virus without relying on stress granule formation.

DOI 10.1038/s41598-026-62049-6

humanimaging

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ImmunologybioRxivPreprintJul 12, 2025

Stress granule component TIA-1 is a specific negative regulator of the non-canonical NLRP3 inflammasome.

Prem Prasad Lamichhane, Aditi Aditi, Blake H. Neil…·Parimal Samir

This study identifies TIA-1 as a negative regulator of the non-canonical NLRP3 inflammasome, showing its role in suppressing LPS-induced inflammation and endotoxic shock.

2 citations

mouseexperimental assay

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