Parimal Samir

The paper screens TLR signaling inhibitors to identify compounds affecting stress granules and finds PPM18, which inhibits Influenza A Virus without relying on stress granule formation.

This study identifies TIA-1 as a negative regulator of the non-canonical NLRP3 inflammasome, showing its role in suppressing LPS-induced inflammation and endotoxic shock.

This study shows RSV infection protects against SARS-CoV-2 by boosting γδ T cell immunity and mucosal T cell responses in mice.

This study uses a murine model to investigate persistent neurological symptoms after SARS-CoV-2 Delta variant infection, finding long-term immune activation and behavioral abnormalities.

This study identifies Snip1 as a regulator of neural progenitor cell fates by interacting with PRC2 to control apoptosis, cell division, and neurogenesis in the developing mouse brain.