Ashok K. Chopra

Combination of live attenuated and adenovirus-based vaccines completely protects interferon gamma (IFNγ) knockout mice against pneumonic plague

This study evaluates two live attenuated plague vaccines and their combination with an adenovirus-based vaccine in IFNγ knockout mice, showing complete protection against pneumonic plague.

Stress granule component TIA-1 is a specific negative regulator of the non-canonical NLRP3 inflammasome.

This study identifies TIA-1 as a negative regulator of the non-canonical NLRP3 inflammasome, showing its role in suppressing LPS-induced inflammation and endotoxic shock.

A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID-19-Flu Mucosal Vaccines

This paper describes a bacteriophage T4-based nanoparticle platform for designing dual COVID-19-Flu mucosal vaccines, showing robust immune responses and protection in mice.