Marius Christian Hoener

This study examines the effects of TAAR2-9 knockout on sleep/wake patterns in mice, finding altered REM sleep and wakefulness but no difference in homeostatic response to sleep loss.

This study shows that TAAR1 partial agonism increases wakefulness and reduces NREM sleep in mice, with D1R and D2R antagonists modulating these effects differently.

This study shows that activating TAAR1 reduces alcohol consumption in mice, suggesting it as a potential target for treating alcohol abuse.

The paper identifies a potent ASO targeting UBE3A-ATS in Angelman syndrome patient neurons, showing long-lasting effects in cynomolgus monkeys.