Author

Jasmine Heu

SRI InternationalORCID 0000-0002-4357-2573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 4 Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sunmee ParkiD· 4 shared Thomas S. KilduffiD· 4 shared Meghan HaireiD· 3 shared Ryan K. TisdaleiD· 3 shared Shun‐Chieh MaiD· 3 shared Yu SuniD· 3 shared Marius Christian HoeneriD· 2 shared Stephen R. MorairtyiD· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersNeuroscience

Sunmee ParkORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TAAR2-9 Knockout Mice Exhibit Reduced Wakefulness and Disrupted REM Sleep

Sunmee Park, Jasmine Heu, Gavin Scheldrup, Ryan K. Tisdale, Yu Sun, Meghan Haire, Shun‐Chieh Ma, Marius Christian Hoener, Thomas S. Kilduff

This study examines the effects of TAAR2-9 knockout on sleep/wake patterns in mice, finding altered REM sleep and wakefulness but no difference in homeostatic response to sleep loss.

bioRxiv · Sep 9, 2024 · PreprintNeuroscience

Wakefulness induced by TAAR1 partial agonism is mediated through dopaminergic neurotransmission

Sunmee Park, Jasmine Heu, Marius Christian Hoener, Thomas S. Kilduff

This study shows that TAAR1 partial agonism increases wakefulness and reduces NREM sleep in mice, with D1R and D2R antagonists modulating these effects differently.

bioRxiv · Sep 9, 2024 · PreprintNeuroscience

Evaluation of the Efficacy of the Hypocretin/orexin Receptor Agonists TAK-925 and ARN-776 in Narcoleptic Orexin/tTA; TetO-DTA Mice

Yu Sun, Alok Ranjan, Ryan K. Tisdale, Shun‐Chieh Ma, Sunmee Park, Meghan Haire, Jasmine Heu, Stephen R. Morairty, Xiaoyu Wang, Daniel M. Rosenbaum, Noelle Sevilir Williams, Jef K. De Brabander, Thomas S. Kilduff

This study evaluates the efficacy of TAK-925 and ARN-776, HCRTR2 agonists, in reducing cataplexy and promoting wakefulness in narcoleptic mice.

bioRxiv · Dec 9, 2022 · PreprintNeuroscience

The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice

Yu Sun, Ryan K. Tisdale, Sunmee Park, Shun‐Chieh Ma, Jasmine Heu, Meghan Haire, Giancarlo Allocca, Akihiro Yamanaka, Stephen R. Morairty, Thomas S. Kilduff

This study compares the development of narcoleptic symptoms in male and female orexin-tTA; TetO-DTA mice, finding females develop symptoms faster but both sexes show similar symptoms by week 6.

SLEEP · Feb 19, 2022Peer-reviewedNeuroscience