Caroline I. Fandrey

This paper introduces Transposon-Display, a method to identify and optimize AI-designed protein binders for intracellular use, enabling controlled protein manipulation in human cells.

This paper develops AI-designed protein binders for cancer cell surface proteins, showing their effectiveness in detection and targeting through experimental validation and benchmarking of structure prediction models.

This paper introduces CRISPR-READ, a live cell RNA sensor that detects endogenous transcripts and identifies Type-I interferon signaling through RNA-seq of sorted cells.

The paper introduces NIS-Seq, a method for genome-scale optical perturbation screening in any nucleus-containing cell type, and demonstrates its application in identifying inflammation-related pathway components.