Author
University of BonnORCID 0009-0007-0173-2026Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Elisabeth Tan, Sophie C Frechen, Bianca Broske…·Gregor Hagelueken
This paper combines evolutionary algorithms with AI to design potent Nectin-4-specific cancer biologics, achieving high-affinity minibinders and functional reagents.
Yuqi Tan, Tim Noah Kempchen, Martin Becker…·Garry P. Nolan
SPACEc provides a Python workflow for analyzing multiplexed imaging data with interactive tools for image processing, segmentation, and spatial analysis.
Maximilian Haist, Magdalena Matusiak, Yuqi Tan…·Garry P. Nolan
The paper identifies spatial immune patterns in Merkel cell carcinoma linked to viral status and patient outcomes.
Alexander Hoch, Caroline I. Fandrey, Brian Coventry…·Jonathan Leo Schmid-Burgk
This paper introduces Transposon-Display, a method to identify and optimize AI-designed protein binders for intracellular use, enabling controlled protein manipulation in human cells.
Bianca Broske, Sophie C. Binder, Benjamin A. McEnroe…·Michael Hölzel
This paper develops AI-designed protein binders for cancer cell surface proteins, showing their effectiveness in detection and targeting through experimental validation and benchmarking of structure prediction models.
Dillon Corvino, Martin Druce Batstone, Brett G.M. Hughes…·Tobias Bald
The paper identifies a subset of CD8+ TILs in HPV-HNSCC enriched for interferon-stimulated genes that are transcriptionally inert to TCR stimulation and may hinder T-cell differentiation.