Author

J. Carlos Angel

La Jolla Institute for ImmunologyORCID 0000-0001-6531-7381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anjana RaoiD· 3 shared Aurélie Modat· 2 shared Geoffrey J. FaulkneriD· 2 shared Hugo SepúlvedaiD· 2 shared Isaac F. López-MoyadoiD· 2 shared Lot Hernández-EspinosaiD· 2 shared Robert CrawfordiD· 2 shared Xiaojing Yue· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

Anjana RaoORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 11, 2026

Flanking DNA sequences determine DNA methylation maintenance in proliferation, cancer and aging

Isaac F. López-Moyado, Lot Hernández-Espinosa, J. Carlos Angel…·Anjana Rao

The paper identifies DNA hexanucleotide sequences that determine DNA methylation maintenance across cell divisions, revealing their role in biological age and cancer progression.

1 citation

DNA methylationstatistical model

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NeurosciencebioRxivPreprintOct 29, 2025

Crosstalk between the Methyl-Cytosine Dioxygenase TET3 and the Methyl-CpG-binding protein MECP2 Controls Neuronal Maturation

Franziska R. Traube, Gilles Gasparoni, Anna Winkler…·Stylianos Michalakis

The paper shows TET3 and MECP2 interact to regulate neuronal maturation, with TET3 critical for functional development and MECP2 inhibiting TET3 activity.

DOI 10.1101/2025.10.29.685266

humanbulk RNA-seq

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedMar 28, 2025

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepúlveda, Xiang Li, Leo J. Arteaga-Vazquez…·Anjana Rao

This study shows that OGT inhibits TET activity, preventing DNA demethylation and transposable element expression in heterochromatin.

25 citationstop 2%

mouseDNA methylation

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