Farhang Jaryani

MosaicSim simulates mosaic variants in sequencing data to evaluate detection methods, showing that higher coverage improves detection rates without false positives.

This study investigates EZHIP mutations in pediatric brain tumors, showing their presence in new tumor types and revealing their role in neuronal-like gene programs and polyamine metabolism repression.

DesiRNA designs RNA sequences with a Monte Carlo approach, considering structural and sequence constraints, and performs well on the EteRNA benchmark.