GeneticsGeroSciencePeer-reviewed
Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1 independent transcriptional response.
Joseph C.P. Kruempel, Hillary A. Miller, Megan L. Schaller…·Scott F. Leiser
This study shows that mutations in egl-9 and rhy-1 suppress the long-lived phenotype of vhl-1 mutants in C. elegans, indicating a VHL-1-independent role for EGL-9 and RHY-1 in longevity regulation.
11 citations