Nicholas A. Olimpo

This study shows that IL15/IL15Rα complex with radiation therapy requires Treg depletion to induce anti-tumor immunity and that PD1-IL2v enhances CD8 T cell activation and function.

This study shows that combining immunotherapies can lead to divergent tumor responses based on the tumor microenvironment, with Treg depletion reversing progression in pancreatic cancer.

This study shows that targeting the EphB4-ephrinB2 axis with engineered ligands reduces metastasis in HNSCC by modulating tumor microenvironment and immune responses.

This study investigates the dual role of EphA4 in T regulatory cells and tumor-associated macrophages during HNSCC progression, showing pro-tumoral and anti-tumoral effects respectively.

This study shows that adolescent social isolation increases cocaine-seeking behavior and alters reward-related brain circuitry in mice.