Author

Miles Piper

University of Colorado AnschutzORCID 0000-0002-8458-2524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony J. SaviolaiD· 2 shared Chloe A. HodgsoniD· 2 shared Christian KleiniD· 2 shared Jacob GadwaiD· 2 shared Justin YuiD· 2 shared Maria AmanniD· 2 shared Michael W. KnitziD· 2 shared Nicholas A. OlimpoiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Anthony J. SaviolaORCID

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2 papers

Recent·Most cited

Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewedSep 2, 2025

IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells

Miles Piper, Chloe A. Hodgson, Jacob Gadwa…·Sana D. Karam

This study shows that IL15/IL15Rα complex with radiation therapy requires Treg depletion to induce anti-tumor immunity and that PD1-IL2v enhances CD8 T cell activation and function.

1 citation

mouseproteomics

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ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedJan 1, 2025

Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

Jacob Gadwa, Justin Yu, Miles Piper…·Sana D. Karam

This study shows that combining immunotherapies can lead to divergent tumor responses based on the tumor microenvironment, with Treg depletion reversing progression in pancreatic cancer.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky